SALT COMPOSITION

Pregabalin (75mg) + Nortriptyline (10mg)

STORAGE

Store at room temperature (10-30°C)

INTRODUCTION

Prejulin NT 75mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Prejulin NT 75mg/10mg Tablet is taken by mouth, with or without food and preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop this medication suddenly without talking to the doctor.
Some common side effects of this medicine include constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

 USES OF PREJULIN NT TABLET

• Neuropathic pain

BENEFITS OF PREJULIN NT TABLET

In Neuropathic pain

Prejulin NT 75mg/10mg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Taking Prejulin NT 75mg/10mg Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

 SIDE EFFECTS OF PREJULIN NT TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prejulin NT

• Constipation
• Difficulty in urination
• Weight gain
• Sleepiness
• Dizziness
• Tiredness
• Blurred vision
• Dryness in mouth
• Increased heart rate
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Uncoordinated body movements

HOW TO USE PREJULIN NT TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prejulin NT 75mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

 HOW PREJULIN NT TABLET WORKS

Prejulin NT 75mg/10mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

 SAFETY ADVICE

Alcohol

UNSAFE

Prejulin NT 75mg/10mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Prejulin NT 75mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

Prejulin NT 75mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Prejulin NT 75mg/10mg Tablet may cause side effects which could affect your ability to drive.
As Prejulin NT 75mg/10mg Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Prejulin NT 75mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Prejulin NT 75mg/10mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Prejulin NT 75mg/10mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Prejulin NT 75mg/10mg Tablet may not be needed in these patients. Please consult your doctor.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS